N. Siva Kumar, a Senior Professor in Biochemistry is an independent researcher, an eminent teacher for 35 years. His academic accomplishments are exceptional. With expertise in the area of protein biochemistry, glycobiology, the nominee developed new affinity
methods, purified several biologically important proteins from legume and non-legume seeds
(lectins, glycosidases, their glycan structures analysed) and established their structure-
function relationships. His initial hypothesis on understanding the physiological and
evolutionary significance of Mannose 6-phosphate receptors (MPR 46 and 300) in lysosomal
biogenesis, in the animal kingdom. His work unequivocally confirmed that the MPR 46 is the
most ancient receptor in evolution and MPR300 evolved by gene duplication in the higher
organisms. Major contributions including the phosphomannooligosaccharide and lysosomal
enzyme nanoparticles preparation has potential for use in drug delivery systems. He had mentored several postdocs, 20 Ph.Ds, including Dr. Mohamad Javed Ali, Bhatnagar Awardee, has worked
on Glycobiology of human lacrimal gland.